Itraconazole Salep. Itraconazole and its major metabolite hydroxyitraconazole can inhibit the metabolism of drugs metabolised by the cytochrome 3A family (CYP3A4) and can inhibit the drug transport by Pglycoprotein which may result in increased plasma concentrations of these drugs and/or their active metabolite(s) when they are administered with itraconazole The effect of itraconazole in increasing the AUC of.
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Itraconazole must not be used during pregnancy except in lifethreatening situations (see section 46) Itraconazole should not be administered to patients with evidence of ventricular dysfunction such as congestive heart failure (CHF) or a history of CHF except for the treatment of lifethreatening or other serious infections (see section 44).
Itraconazole 10 mg/ml Oral Solution Summary of Product
Itraconazole has important interactions with other medications As itraconazole needs acid for its absorption antacids H2 antagonists (cimetidine famotidine ranitidine) and omeprazole should not be taken for 2 hours after itraconazoleItraconazole is a Pglycoprotein inhibitor and increases the concentration of some drugs.
ITRACONAZOLE Drug BNF content published by NICE
Itraconazole and its major metabolite hydroxyitraconazole can inhibit the metabolism of drugs metabolised by CYP3A4 and can inhibit the drug transport by Pglycoprotein which may result in increased plasma concentrations of these drugs and/or their active metabolite(s) when they are administered with itraconazole These elevated plasma concentrations may increase or prolong both.
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Itraconazole 100 mg Capsules Summary of Product
of Product Itraconazole 100mg Capsules, hard Summary
NZ Itraconazole DermNet
There have been reports of heart failure associated with itraconazole Those at risk may include patients receiving higher daily doses and longer courses patients with cardiac disease patients with chronic lung disease and patients receiving treatment with calcium channel blockers Manufacturer advises avoid in patients with ventricular dysfunction such as history of congestive heart.
