Rifampicin Isoniazid Pyrazinamide Ethambutol Hydrochloride Tablets. Each Blister combi pack contains Z=Pyrazinamide Tablets IP (2 Tablets ) Each uncoated tablet contains Pyrazinamide IP 750 mg Excipients QS E = Ethambutol Hydrochloride and Isoniazid Tablet ( 1 Tablet) Each uncoated tablet contains Ethambutol Hydrochloride IP 800 mg Isoniazid IP 300 mg Excipients QS R = Rifampicin Capsule IP ( 1 capsule) Each capsule contains .

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BDDCS AND ITS USE In 1995 Wu and Benet reviewed 131 drugs that had been classified into the four BCS categories in the literature through the end of 1994Ten of these drugs had been listed in different classes by different authors Wu and Benet recognized that the major route of elimination in humans for the great majority of highpermeability class 1 and class 2.

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Isoniazid is a bactericidal agent active against organisms of the genus Mycobacterium specifically M tuberculosis M bovis and M kansasii It is a highly specific agent ineffective against other microorganisms Isoniazid is bactericidal when mycobacteria grow rapidly and bacteriostatic when they grow slowly Mechanism of action.

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